Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 2/20 | 0.30 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450833 | 0.97 | CNR1 (0.32) | GRM2 | |
| SCHEMBL8963255 | 0.94 | EP300 (0.32) | KCNH2 | |
| SCHEMBL8963262 | 0.94 | EP300 (0.32) | KCNH2 | |
| SCHEMBL8963053 | 0.93 | KCNH2 (0.33) | KCNH2FPR2PROKR1 | |
| SCHEMBL8963047 | 0.93 | KCNH2 (0.33) | KCNH2FPR2PROKR1 | |
| SCHEMBL8963287 | 0.89 | PROKR1 (0.33) | KCNH2FPR2PROKR1 | |
| SCHEMBL8963292 | 0.89 | PROKR1 (0.33) | KCNH2FPR2PROKR1 | |
| SCHEMBL8962798 | 0.82 | CNR1 (0.36) | — | |
| SCHEMBL8962799 | 0.82 | CNR1 (0.36) | — | |
| SCHEMBL9265783 | 0.79 | PROKR1 (0.35) | KCNH2FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007234-A1 | HALOVINYL-DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-15 | — | — | WO | disclosed |