SCHEMBL9540865

SCHEMBL9540865

CC(C)OC(=O)c1sc2nc3ccccc3c(O)c2c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.49
KMT2A Q03164 7/20 0.49
HPGD P15428 7/20 0.49
KDM4E B2RXH2 6/20 0.49
MEN1 O00255 6/20 0.49
MAPT P10636 6/20 0.49
RAB9A P51151 4/20 0.49
NPC1 O15118 3/20 0.49
ATM Q13315 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
TLR9 Q9NR96 1/20 0.49
CACNA1B Q00975 2/20 0.43
APBA1 Q02410 2/20 0.43
POLB P06746 2/20 0.42
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9542399 0.89 ALDH1A1 (0.47) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL9541066 0.88 ALDH1A1 (0.46) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL9541407 0.81 ALDH1A1 (0.50) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL9541080 0.75 KDM4E (0.47) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL9540885 0.74 KDM4E (0.47) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL9944375 0.73 MEN1 (0.58) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL9541119 0.73 KMT2A (0.46) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL9543715 0.73 ALDH1A1 (0.41) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL10413476 0.69 PDCD1 (0.51) ALDH1A1KMT2AHPGDKDM4EMEN1
SCHEMBL30881961 0.66 CA12 (0.59) ALDH1A1KMT2AHPGDKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013664-A2 BIHETEROCYCLIC FUNGICIDAL COMPOUNDS SCHERING AGROCHEMICALS LIMITED (GB) 1993-07-22 WO disclosed