SCHEMBL9541407

SCHEMBL9541407

CC(C)OC(=O)c1sc2nc3ccccc3cc2c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.50
KDM4E B2RXH2 7/20 0.50
HPGD P15428 5/20 0.50
MAPT P10636 5/20 0.50
RAB9A P51151 4/20 0.50
KMT2A Q03164 4/20 0.50
NPC1 O15118 3/20 0.50
MEN1 O00255 3/20 0.50
ATM Q13315 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TLR9 Q9NR96 1/20 0.50
LMNA P02545 2/20 0.40
TP53 P04637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CACNA1B Q00975 2/20 0.39
APBA1 Q02410 2/20 0.39
SLC14A1 Q13336 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9540865 0.81 ALDH1A1 (0.49) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL9541204 0.81 NSD2 (0.42) ALDH1A1KDM4EHPGDMAPTKMT2A
SCHEMBL9542399 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL13954996 0.77 MAPT (0.47) ALDH1A1KDM4EMAPTRAB9AKMT2A
SCHEMBL9541066 0.77 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL9541191 0.76 KMT2A (0.42) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL9540885 0.75 KDM4E (0.47) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL12562465 0.70 SLC14A1 (0.71) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL11001442 0.69 NPC1 (0.57) ALDH1A1KDM4EHPGDMAPTRAB9A
SCHEMBL29912577 0.69 NPC1 (0.57) ALDH1A1KDM4EHPGDMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013664-A2 BIHETEROCYCLIC FUNGICIDAL COMPOUNDS SCHERING AGROCHEMICALS LIMITED (GB) 1993-07-22 WO disclosed