Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576430 | 0.86 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL15843878 | 0.85 | ALDH1A1 (0.45) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL15843879 | 0.85 | ALDH1A1 (0.45) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL15843720 | 0.80 | NAAA (0.44) | ALDH1A1ATMTSHRHCAR2NAAA | |
| SCHEMBL15843719 | 0.80 | NAAA (0.44) | ALDH1A1ATMTSHRHCAR2NAAA | |
| SCHEMBL5138405 | 0.80 | NAAA (0.56) | ALDH1A1ATMTSHRHCAR2NAAA | |
| SCHEMBL15843756 | 0.79 | NAAA (0.47) | ALDH1A1TSHRHCAR2NAAAEPHX1 | |
| SCHEMBL15843481 | 0.79 | NAAA (0.47) | ALDH1A1TSHRHCAR2NAAAEPHX1 | |
| SCHEMBL15843493 | 0.79 | NAAA (0.47) | ALDH1A1TSHRHCAR2NAAAEPHX1 | |
| SCHEMBL15864647 | 0.79 | NAAA (0.47) | ALDH1A1TSHRHCAR2NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009794-A1 | SUPPRESSION OF MEGAKARYOCYTOPOIESIS BY NEUTROPHIL ACTIVATING PEPTIDE-2 | UNIVERSITY OF PENNSYLVANIA (US) | 1993-05-27 | — | — | WO | disclosed |