Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131369 | 0.80 | MAPT (0.60) | MAPTNPC1RAB9APOLBOPRK1 | |
| SCHEMBL9541065 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL9540942 | 0.75 | MAPT (0.54) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL9541076 | 0.72 | ALDH1A1 (0.47) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL9542497 | 0.72 | ALDH1A1 (0.47) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL9541191 | 0.70 | KMT2A (0.42) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL9540994 | 0.70 | ALDH1A1 (0.46) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL9542510 | 0.70 | ALDH1A1 (0.47) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL27403724 | 0.69 | ALDH1A1 (0.44) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL9540890 | 0.68 | ALDH1A1 (0.43) | MAPTNPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |