Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455530 | 1.00 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9540930 | 1.00 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL6930553 | 0.79 | NPC1 (0.51) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL14617619 | 0.78 | MAPT (0.54) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL7888883 | 0.76 | ALDH1A1 (0.73) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL10448311 | 0.73 | G6PD (0.47) | ALDH1A1NPC1RAB9AMAPTG6PD | |
| SCHEMBL1404289 | 0.73 | G6PD (0.47) | ALDH1A1NPC1RAB9AMAPTG6PD | |
| SCHEMBL22575907 | 0.73 | G6PD (0.47) | ALDH1A1NPC1RAB9AMAPTG6PD | |
| SCHEMBL11527494 | 0.72 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL11526331 | 0.72 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007879-A1 | HETEROCYCLIC BISPHOSPHONIC ACID DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-29 | — | — | WO | disclosed |
| US-5128328-A | Treatment of osteoporosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-07-07 | — | — | US | disclosed |