Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541015 | 0.72 | AKR1B1 (0.43) | NPSR1ADRA1AMAPTALDH1A1HPGD | |
| SCHEMBL9541026 | 0.69 | LTB4R (0.40) | PDPK1PTGDR2FFAR4 | |
| SCHEMBL19865372 | 0.69 | HPGD (0.50) | GPR17NPSR1PTGDR2FFAR1FFAR4 | |
| SCHEMBL7544691 | 0.68 | PTGDR2 (0.41) | HTR1AADRA2ADRD2ADRA2BADRA2C | |
| SCHEMBL28387747 | 0.67 | PTGDR2 (0.53) | PDPK1GPR17NPSR1PTGDR2FFAR1 | |
| SCHEMBL14430303 | 0.67 | PDPK1 (0.47) | PDPK1GPR17NPSR1PTGDR2FFAR1 | |
| SCHEMBL18397695 | 0.67 | APEX1 (0.51) | GPR17NPSR1PTGDR2KEAP1FFAR1 | |
| SCHEMBL29604377 | 0.67 | PDPK1 (0.47) | PDPK1GPR17NPSR1PTGDR2FFAR1 | |
| SCHEMBL31690287 | 0.67 | NPSR1 (0.44) | GPR17NPSR1PTGDR2FFAR1FFAR4 | |
| SCHEMBL28651618 | 0.66 | NPSR1 (0.47) | PDPK1GPR17NPSR1PTGDR2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |