⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805983 | 0.70 | — | — | |
| SCHEMBL877009 | 0.69 | — | — | |
| SCHEMBL8760590 | 0.69 | — | — | |
| SCHEMBL1650435 | 0.65 | — | — | |
| SCHEMBL16308845 | 0.65 | LMNA (0.40) | — | |
| SCHEMBL176452 | 0.63 | PPARG (0.64) | — | |
| SCHEMBL7056294 | 0.63 | LMNA (0.53) | — | |
| SCHEMBL176453 | 0.63 | PPARG (0.64) | — | |
| SCHEMBL2540034 | 0.63 | PPARG (0.64) | — | |
| Ethylene SCHEMBL27637339 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011277-A1 | INHIBITOR(S) OF TRANSPORTERS OR UPTAKE OF MONOAMINERGIC NEUROTRANSMITTERS | STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| US-8772330-B2 | Inhibitor(s) of transporters or uptake of monoaminergic neurotransmitters | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120190725-A1 | INHIBITOR(S) OF TRANSPORTERS OR UPTAKE OF MONOAMINERGIC NEUROTRANSMITTERS | STATE UNIVERSITY | 2012-07-26 | — | — | US | disclosed |
| WO-2011011277-A1 | INHIBITOR(S) OF TRANSPORTERS OR UPTAKE OF MONOAMINERGIC NEUROTRANSMITTERS | STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2011-01-27 | — | — | WO | disclosed |