Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481117 | 0.88 | HPGD (0.53) | KDM4ECYP4F2CYP4A11ALDH1A1CA12 | |
| SCHEMBL27089477 | 0.83 | HPGD (0.49) | KDM4ECYP4F2CYP4A11ALDH1A1CA12 | |
| SCHEMBL13870603 | 0.83 | CYP4F2 (0.51) | KDM4ECYP4F2CYP4A11ALDH1A1CA12 | |
| SCHEMBL7765079 | 0.82 | TSHR (0.58) | KDM4EALDH1A1PKMCA12CA1 | |
| SCHEMBL5238335 | 0.81 | SMN1; SMN2 (0.51) | KDM4ECYP4F2CYP4A11ALDH1A1CA12 | |
| SCHEMBL1702411 | 0.81 | CYP4F2 (0.66) | CYP4F2CYP4A11ALDH1A1CA12CA1 | |
| SCHEMBL8322496 | 0.81 | HPGD (0.50) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL9541238 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1PKMCA12CA1 | |
| SCHEMBL11378327 | 0.80 | KDM4E (0.44) | KDM4ECYP4F2CYP4A11ALDH1A1PKM | |
| SCHEMBL5250038 | 0.80 | CYP4F2 (0.56) | KDM4ECYP4F2CYP4A11PKMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |