Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11382505 | 0.89 | KDM4E (0.44) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL14157079 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1TP53MAPTMAPK1 | |
| SCHEMBL9541197 | 0.80 | KDM4E (0.51) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL15835741 | 0.77 | LMNA (0.50) | HPGDHSD17B10GAAALDH1A1MAPT | |
| SCHEMBL10517001 | 0.77 | MAPK1 (0.48) | KDM4EHPGDMAPTMAPK1CA12 | |
| SCHEMBL11375452 | 0.76 | DPP4 (0.46) | GAAALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL6904947 | 0.75 | TBXAS1 (0.53) | HPGDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3481117 | 0.74 | HPGD (0.53) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL8322496 | 0.74 | HPGD (0.50) | KDM4EHPGDHSD17B10GAAALDH1A1 | |
| SCHEMBL10565958 | 0.74 | ALDH1A1 (0.46) | KDM4EHPGDGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273773-A | IN COMBINATION WITH A DIURETIC | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |