Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293855 | 0.82 | KDM4E (0.37) | ALDH1A1KDM4EHPGDPOLBALOX12 | |
| SCHEMBL9736523 | 0.78 | SLC6A4 (0.39) | ALDH1A1KDM4ESLC6A4DRD3SLC6A2 | |
| SCHEMBL30187749 | 0.78 | SLC6A4 (0.46) | ALDH1A1SLC6A4DRD3SLC6A2HTR2C | |
| SCHEMBL2817157 | 0.78 | SLC6A4 (0.46) | ALDH1A1SLC6A4DRD3SLC6A2HTR2C | |
| SCHEMBL12715536 | 0.77 | POLB (0.46) | ALDH1A1POLBDRD3DRD2PNMT | |
| SCHEMBL15147627 | 0.76 | KDM1A (0.41) | ALDH1A1SLC6A4DRD3DRD2SLC6A2 | |
| SCHEMBL10164910 | 0.75 | MAOB (0.42) | KDM4EPOLBDRD3DRD2PNMT | |
| SCHEMBL31545183 | 0.72 | PNMT (0.48) | ALDH1A1SLC6A4DRD3DRD2SLC6A2 | |
| SCHEMBL2809825 | 0.72 | PNMT (0.48) | ALDH1A1SLC6A4DRD3DRD2SLC6A2 | |
| SCHEMBL1097697 | 0.70 | UTS2R (0.39) | ALDH1A1KDM4EHPGDPOLBALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993004182-A1 | PROCESS FOR THE PREPARATION OF 3,4-EPOXY BENZOPYRANS AND PYRANOPYRIDINES BY A MICROBIAL EPOXIDASE | SMITHKLINE BEECHAM PLC (GB) | 1993-03-04 | — | — | WO | disclosed |