SCHEMBL9541239

SCHEMBL9541239

[CH2]CC(C)(C)Cc1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
SSTR4 P31391 1/20 0.37
CHRM2 P08172 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
ACHE P22303 2/20 0.36
TSHR P16473 2/20 0.36
KMT2A Q03164 1/20 0.35
CYP2A13 Q16696 1/20 0.34
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
NR3C2 P08235 1/20 0.34
HPGD P15428 2/20 0.33
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CTBP2 P56545 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
NR3C1 P04150 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2958719 0.79 TAAR1 (0.42) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL20746223 0.79 TAAR1 (0.52) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL3167835 0.78 RIPK1 (0.48) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL23852496 0.76 TAAR1 (0.39) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL7733342 0.76 TAAR1 (0.39) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL808983 0.74 TAAR1 (0.45) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL3638610 0.74 TAAR1 (0.52) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL15976426 0.74 TAAR1 (0.45) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL19085950 0.74 TAAR1 (0.45) TAAR1SSTR4CHRM2PTGS1PTGS2
SCHEMBL13722854 0.74 TAAR1 (0.45) TAAR1SSTR4CHRM2PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013089-A1 MACROCYCLIC POLYETHER CARBOXYLIC ACIDS URBAN FRANK J (US) 1993-07-08 WO disclosed