SCHEMBL2958719

SCHEMBL2958719

Cc1ccccc1CC(C)(C)CO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
SSTR4 P31391 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
HPGD P15428 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CTBP2 P56545 1/20 0.37
NR3C2 P08235 1/20 0.37
TSHR P16473 3/20 0.36
LMNA P02545 2/20 0.36
KMT2A Q03164 2/20 0.36
ATM Q13315 2/20 0.36
CHRM2 P08172 1/20 0.36
MEN1 O00255 1/20 0.36
GMNN O75496 1/20 0.36
GABBR2 O75899 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23852496 0.80 TAAR1 (0.39) TAAR1SSTR4ADRB2ADRB1HPGD
SCHEMBL9541239 0.79 TAAR1 (0.42) TAAR1SSTR4ADRB2ADRB1HPGD
SCHEMBL17051292 0.79 PDCD1 (0.37) TAAR1ALDH1A1TSHRLMNAKMT2A
SCHEMBL20512217 0.79 HSPA5 (0.48) TAAR1ALDH1A1TSHRLMNAKMT2A
SCHEMBL20746223 0.79 TAAR1 (0.52) TAAR1SSTR4ADRB2ADRB1HPGD
SCHEMBL808983 0.78 TAAR1 (0.45) TAAR1SSTR4ADRB2ADRB1HPGD
SCHEMBL13722854 0.78 TAAR1 (0.45) TAAR1SSTR4ADRB2ADRB1HPGD
SCHEMBL15976426 0.78 TAAR1 (0.45) TAAR1SSTR4ADRB2ADRB1HPGD
SCHEMBL3167835 0.78 RIPK1 (0.48) TAAR1SSTR4ADRB2ADRB1HPGD
SCHEMBL18325596 0.78 DPP4 (0.41) TAAR1ALDH1A1TSHRLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3122847-A1 PERFUME SYSTEMS The Procter & Gamble Company (US) 2017-02-01 EP claimed
EP-1474095-B2 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTRE (US) 2016-12-21 EP claimed
US-20160289593-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2016-10-06 US claimed
WO-2015148743-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2015-10-01 WO claimed
US-20150275132-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY 2015-10-01 US claimed
EP-1474095-B1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTRE (US) 2013-06-12 EP claimed
EP-2581077-A2 Olfactory adaption and cross-adapting agents to reduce the perception of body odors Symrise AG (DE) 2013-04-17 EP claimed
US-20100254927-A1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTER (US) 2010-10-07 US claimed
US-20070020210-A1 Methods of reducing the perception of body odors with olfactory adaptation and cross-adapting agents MONELL CHEMICAL SENSES CENTER 2007-01-25 US claimed
EP-3521409-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2024-08-14 EP disclosed
US-20240225915-A1 COMPOSITIONS FOR FIGHTING MALODORS SYMRISE AG (DE) 2024-07-11 US disclosed
EP-4351667-A1 COMPOSITIONS FOR FIGHTING MALODORS Symrise AG (DE) 2024-04-17 EP disclosed
WO-2022258189-A1 COMPOSITIONS FOR FIGHTING MALODORS SYMRISE AG (DE) 2022-12-15 WO disclosed
EP-3521409-A2 PERFUME SYSTEMS The Procter & Gamble Company (US) 2019-08-07 EP disclosed
US-7763238-B2 Olfactory adaptation and cross-adapting agents to reduce the perception of body odors MONELL CHEMICAL SENSES CENTER (US) 2010-07-27 US disclosed
EP-1474095-A4 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTRE (US) 2007-11-28 EP disclosed
US-20070020210-A1 Methods of reducing the perception of body odors with olfactory adaptation and cross-adapting agents MONELL CHEMICAL SENSES CENTER 2007-01-25 US disclosed
EP-1474095-A1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTER (US) 2004-11-10 EP disclosed
US-20030152538-A1 Olfactory adaptation and cross-adapting agents to reduce the perception of body odors SYMRISE INC. 2003-08-14 US disclosed
WO-2003061609-A1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTER (US) 2003-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289593-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 TAAR1 615/4885SSTR4 2383/4885ADRB2 438/4885
US-20150275132-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 TAAR1 615/4885SSTR4 2383/4885ADRB2 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.