Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585790 | 0.84 | LMNA (0.44) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL6354255 | 0.84 | TSHR (0.59) | TSHRALDH1A1HSD17B10CLEC4MPLK1 | |
| SCHEMBL8724253 | 0.83 | TSHR (0.58) | TSHRALDH1A1HSD17B10CLEC4MPLK1 | |
| SCHEMBL30772831 | 0.83 | TSHR (0.58) | TSHRALDH1A1HSD17B10CLEC4MPLK1 | |
| SCHEMBL2601357 | 0.81 | CYP4F2 (0.56) | TSHRALDH1A1HSD17B10CLEC4MPLK1 | |
| SCHEMBL5250458 | 0.81 | TSHR (0.56) | TSHRALDH1A1HSD17B10CLEC4MPLK1 | |
| SCHEMBL1656703 | 0.80 | TSHR (0.63) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL995737 | 0.80 | TSHR (0.74) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL4627106 | 0.79 | TSHR (0.61) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL23803712 | 0.78 | TSHR (0.59) | TSHRALDH1A1HSD17B10CLEC4MCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |