Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772831 | 1.00 | TSHR (0.58) | TSHRALDH1A1HSD17B10PLK1CDC25B | |
| SCHEMBL6354255 | 0.85 | TSHR (0.59) | TSHRALDH1A1HSD17B10PLK1CDC25B | |
| SCHEMBL6355411 | 0.85 | TSHR (0.51) | TSHRALDH1A1HSD17B10CDC25BCYP4F2 | |
| SCHEMBL30041782 | 0.83 | LMNA (0.46) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL436238 | 0.83 | LMNA (0.46) | TSHRALDH1A1HSD17B10CA12CA1 | |
| SCHEMBL9412825 | 0.83 | TSHR (0.53) | TSHRALDH1A1HSD17B10CDC25BCA12 | |
| SCHEMBL2601357 | 0.83 | CYP4F2 (0.56) | TSHRALDH1A1HSD17B10PLK1CDC25B | |
| SCHEMBL5250458 | 0.83 | TSHR (0.56) | TSHRALDH1A1HSD17B10PLK1CDC25B | |
| SCHEMBL9541307 | 0.83 | TSHR (0.56) | TSHRALDH1A1HSD17B10PLK1CDC25B | |
| SCHEMBL265052 | 0.81 | TSHR (0.63) | TSHRALDH1A1HSD17B10CDC25BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1082790-C | Herbicides | RHONE POULENE AGRICULTURE LTD (GB) | 2002-04-17 | — | — | CN | disclosed |
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| CN-1100261-A | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-03-22 | — | — | CN | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |