Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541254 | 0.85 | SHBG (0.39) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9542562 | 0.84 | SHBG (0.41) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9541174 | 0.82 | SHBG (0.46) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9542637 | 0.80 | SHBG (0.43) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9126657 | 0.79 | SHBG (0.48) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9126665 | 0.79 | SHBG (0.48) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9541286 | 0.77 | SHBG (0.49) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9541934 | 0.76 | SHBG (0.46) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9541306 | 0.76 | SHBG (0.33) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9542793 | 0.75 | SHBG (0.45) | SHBGALDH1A1NR3C1PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | claimed |
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |