SCHEMBL9541286

SCHEMBL9541286

CC1=C2C[C@@H](C)[C@@H]3[C@H](CC[C@@]4(C)[C@H]3CC[C@]4(C)O)[C@@]2(C)CC/C1=N\OS(C)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SHBG P04278 9/20 0.49
ALDH1A1 P00352 2/20 0.40
AR P10275 6/20 0.34
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
CYP19A1 P11511 2/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9541248 0.84 SHBG (0.49) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9541174 0.84 SHBG (0.46) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9542766 0.83 SHBG (0.54) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9125965 0.79 SHBG (0.63) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9125973 0.79 SHBG (0.63) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9542907 0.79 SHBG (0.64) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9542643 0.79 SHBG (0.64) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9541316 0.77 SHBG (0.39) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9541934 0.76 SHBG (0.46) SHBGALDH1A1ARNR3C1PGR
SCHEMBL9542793 0.75 SHBG (0.45) SHBGALDH1A1ARNR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013122-A1 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS SCHERING AKTIENGESELLSCHAFT (DE) 1993-07-08 WO claimed
WO-1993013122-A1 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS SCHERING AKTIENGESELLSCHAFT (DE) 1993-07-08 WO disclosed