Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12619157 | 1.00 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4APP | |
| SCHEMBL10150427 | 0.88 | PPARA (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4OXER1 | |
| SCHEMBL27875752 | 0.79 | — | — | |
| SCHEMBL4808526 | 0.78 | — | — | |
| SCHEMBL4808522 | 0.78 | — | — | |
| SCHEMBL19900474 | 0.77 | PPARG (0.47) | — | |
| SCHEMBL10150448 | 0.75 | LMNA (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4APP | |
| SCHEMBL10186720 | 0.75 | CA1 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4APP | |
| SCHEMBL12143891 | 0.75 | CHRNB2 (0.32) | CHRNB2CHRNB4CHRNA3CHRNA4APP | |
| SCHEMBL869529 | 0.75 | LMNA (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |