Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11350666 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HSD17B10MCL1BCL2A1TSHR | |
| SCHEMBL1027580 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRPOLBKDM4E | |
| SCHEMBL9541460 | 0.82 | MCL1 (0.68) | ALDH1A1MCL1BCL2A1TSHRPOLB | |
| SCHEMBL9543995 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRPOLBKDM4E | |
| SCHEMBL2404051 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL31032735 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL11581128 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MCL1TSHRPOLB | |
| SCHEMBL9073929 | 0.77 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2896481 | 0.75 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TSHRSMN1; SMN2NPC1 | |
| SCHEMBL10743287 | 0.75 | CA12 (0.70) | ALDH1A1HSD17B10TSHRKDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |