Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541352 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBHSD17B10KDM4E | |
| SCHEMBL1027580 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTPOLBHSD17B10KDM4E | |
| SCHEMBL11350666 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTPOLBHSD17B10KDM4E | |
| SCHEMBL9541366 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTPOLBHSD17B10KDM4E | |
| SCHEMBL15639611 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTPOLBHSD17B10KDM4E | |
| SCHEMBL13753940 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTPOLBHSD17B10KDM4E | |
| SCHEMBL8422402 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTPOLBHSD17B10KDM4E | |
| SCHEMBL3299507 | 0.76 | CA1 (0.56) | ALDH1A1MAPTGFERTSHRHTT | |
| SCHEMBL9541164 | 0.76 | KDM4E (0.43) | ALDH1A1MAPTPOLBHSD17B10KDM4E | |
| SCHEMBL9541504 | 0.76 | KDM4E (0.43) | ALDH1A1MAPTPOLBHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |