Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | EED | O75530 | 1/20 | 0.52 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.52 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.52 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.52 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18205621 | 0.87 | HPGD (0.61) | KDM4EHPGDCYP1A2PKML3MBTL1 | |
| SCHEMBL24160559 | 0.82 | ALDH1A1 (0.59) | KDM4EHPGDPKMALDH1A1LMNA | |
| SCHEMBL28483635 | 0.82 | ALDH1A1 (0.63) | KDM4EHPGDCYP1A2PKML3MBTL1 | |
| SCHEMBL14682572 | 0.81 | EED (0.55) | KDM4EHPGDEEDRBBP4SUZ12 | |
| SCHEMBL5727441 | 0.79 | HPGD (0.55) | HPGDEEDRBBP4SUZ12EZH2 | |
| SCHEMBL667131 | 0.79 | CTSD (0.72) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL9539904 | 0.78 | KDM4E (0.51) | KDM4EHPGDCYP1A2PKML3MBTL1 | |
| SCHEMBL5954008 | 0.77 | PLK1 (0.54) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL24593411 | 0.77 | UTS2R (0.42) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL31313133 | 0.76 | KDM4E (0.54) | KDM4EHPGDPKML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |