Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 14/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460066 | 0.87 | KDM4E (0.69) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL168327 | 0.84 | KDM4E (0.61) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL4417351 | 0.80 | KDM4E (0.54) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL15745421 | 0.80 | CES2 (0.50) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL30184263 | 0.80 | KDM4E (0.66) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL26057003 | 0.80 | GAA (0.56) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL26020665 | 0.80 | CES2 (0.70) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL26019684 | 0.80 | CES2 (0.50) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL424990 | 0.79 | RXRB (0.70) | ALDH1A1HPGDKDM4EHSD17B10USP2 | |
| SCHEMBL30450981 | 0.79 | KDM4E (0.56) | ALDH1A1HPGDKDM4EHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |
| US-4920224-A | CHEMICAL INTERMEDIATES | PFIZER INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4849518-A | ANTIPROTOZOA IN POULTRY | PFIZER INC. (US) | 1989-07-18 | — | — | US | disclosed |
| US-4762838-A | Quinazolin-4(3H)-one derivatives as anticoccidial agents | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |