Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541521 | 0.81 | POLB (0.53) | POLBLMNAALDH1A1CYP1A2GAA | |
| SCHEMBL18504830 | 0.81 | POLB (0.53) | POLBLMNAALDH1A1CYP1A2GAA | |
| SCHEMBL6418869 | 0.78 | POLB (0.55) | POLBLMNAALDH1A1CYP1A2GAA | |
| SCHEMBL14449300 | 0.78 | POLB (0.59) | POLBLMNAALDH1A1CYP1A2GAA | |
| SCHEMBL24377710 | 0.78 | ALDH1A1 (0.51) | POLBLMNAALDH1A1CYP1A2GAA | |
| SCHEMBL125543 | 0.76 | ALDH1A3 (0.64) | POLBLMNAALDH1A1CYP1A2GAA | |
| SCHEMBL19261529 | 0.76 | TSHR (0.58) | POLBLMNAALDH1A1CYP1A2GAA | |
| SCHEMBL21566809 | 0.76 | POLB (0.49) | POLBLMNAALDH1A1CYP1A2GAA | |
| SCHEMBL153642 | 0.76 | IDO1 (0.61) | POLBALDH1A1RAB9ANPC1PKM | |
| SCHEMBL805120 | 0.76 | POLB (0.57) | POLBLMNAALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013089-A1 | MACROCYCLIC POLYETHER CARBOXYLIC ACIDS | URBAN FRANK J (US) | 1993-07-08 | — | — | WO | disclosed |