Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740682 | 0.78 | LMNA (0.45) | ALDH1A1TSHRHPGDCYP3A4TP53 | |
| SCHEMBL6890534 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRCFTRHPGD | |
| SCHEMBL759012 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRCFTRHPGD | |
| SCHEMBL11451093 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRCFTRHPGD | |
| Hydrochloric Acid SCHEMBL28469611 | 0.75 | ALDH1A1 (0.97) | ALDH1A1HSD17B10TSHRCFTRHPGD | |
| SCHEMBL16672346 | 0.74 | ALDH1A1 (0.71) | ALDH1A1HSD17B10TSHRCFTRHPGD | |
| SCHEMBL6670097 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TSHRCFTRHPGD | |
| SCHEMBL21694738 | 0.71 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRCFTRHPGD | |
| SCHEMBL1501166 | 0.71 | HSD17B10 (0.58) | ALDH1A1HSD17B10TSHRCFTRHPGD | |
| SCHEMBL28166720 | 0.71 | ALDH1A1 (0.67) | ALDH1A1HSD17B10TSHRCFTRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012795-A1 | QUINAZOLIN-4(3H)-ONE DERIVATIVES AS ANTICOCCIDIAL AGENTS | GLAZER EDWARD A (US) | 1993-07-08 | — | — | WO | disclosed |