Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568881 | 0.87 | MAPT (0.47) | MAPTTHRBGAATP53MEN1 | |
| SCHEMBL8566892 | 0.81 | POLB (0.39) | MAPTTHRBGAAPOLBMEN1 | |
| SCHEMBL8567114 | 0.80 | MAPT (0.51) | MAPTTHRBGAATP53MEN1 | |
| Hydrochloric Acid SCHEMBL8561018 | 0.80 | POLB (0.38) | MAPTTHRBGAAPOLBMEN1 | |
| SCHEMBL9541717 | 0.79 | MAPT (0.50) | MAPTTHRBGAASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL9259992 | 0.78 | MAPT (0.49) | MAPTTHRBGAATP53MEN1 | |
| SCHEMBL8564456 | 0.77 | MAPT (0.48) | MAPTTHRBGAASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL8559342 | 0.77 | MAPT (0.47) | MAPTTHRBGAASMN1; SMN2TP53 | |
| SCHEMBL8563378 | 0.76 | PDE4B (0.59) | MAPTTHRBGAASMN1; SMN2TP53 | |
| SCHEMBL8561272 | 0.76 | GAK (0.37) | MAPTTHRBGAASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013097-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |