Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671268 | 0.90 | MAPT (0.53) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL6573912 | 0.90 | MAPT (0.53) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL6570551 | 0.90 | MAPT (0.53) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL6366310 | 0.89 | MAPT (0.51) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL4617844 | 0.86 | MAPT (0.57) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL28142388 | 0.84 | ALDH1A1 (0.64) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL6003995 | 0.82 | MAPT (0.45) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL9362332 | 0.82 | MAPT (0.45) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL3866264 | 0.81 | CA12 (0.57) | MAPTALDH1A1HSD17B10RECQLCA1 | |
| SCHEMBL5119014 | 0.80 | MAPT (0.50) | MAPTALDH1A1HSD17B10RECQLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574094-B | Indolone derivatives and pharmaceutical use thereof | 成都大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-112574094-A | Indolone derivatives and pharmaceutical use thereof | 成都大学 | 2021-03-30 | — | — | CN | disclosed |
| WO-1993010119-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |