Phosphonic Acid

Phosphonic Acid

SCHEMBL9541854

CCC(O)c1ncnn1C(c1ccccc1)(c1ccccc1)c1ccccc1.O=[PH](O)O

nearest known ligand 0.36

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
RECQL P46063 1/20 0.33
ATM Q13315 1/20 0.33
GRIN1 Q05586 4/20 0.30
GRIN2A Q12879 4/20 0.30
GRIN2D O15399 3/20 0.30
GRIN2C Q14957 3/20 0.30
GRIN2B Q13224 2/20 0.30
NR4A3 Q92570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphonic Acid SCHEMBL8386932 0.90 ATM (0.31) ATM
Diethyl Hydrogen Phosphate SCHEMBL27452600 0.83 POLB (0.36) LMNA
SCHEMBL9541851 0.78 ATM (0.30) ATM
SCHEMBL9247999 0.78 ALDH1A1 (0.39) LMNA
SCHEMBL9541657 0.76 ATM (0.34) ATMGRIN1GRIN2AGRIN2DGRIN2C
Phosphonic Acid SCHEMBL8386850 0.76 ATM (0.32) ATM
SCHEMBL9541848 0.75 S1PR2 (0.33) ATM
SCHEMBL8386931 0.75 POLB (0.36)
Phosphonic Acid SCHEMBL9360448 0.73 LMNA (0.35) LMNARECQL
SCHEMBL9251937 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993015610-A1 PHOSPHONIC ACID DERIVATIVES CONTAINING A TRIAZOLE RING AS HERBICIDES ZENECA LIMITED (GB) 1993-08-19 WO disclosed