Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 9/20 | 0.44 |
| ▸ | HTR2A | P28223 | 8/20 | 0.44 |
| ▸ | HTR2B | P41595 | 7/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541908 | 0.79 | MAOB (0.58) | MAOBMAOAHTR2CHTR2AHTR2B | |
| SCHEMBL11593479 | 0.76 | MAOB (0.44) | MAOBMAOASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11591757 | 0.76 | HTR2A (0.46) | MAOBMAOAHTR2CHTR2AHTR2B | |
| SCHEMBL11592202 | 0.71 | HTR2C (0.56) | MAOBMAOAHTR2CHTR2AHTR2B | |
| SCHEMBL11591613 | 0.71 | CHRM2 (0.47) | MAOBMAOASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11593943 | 0.70 | SLC6A4 (0.39) | MAOBMAOASLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11593952 | 0.70 | MAOB (0.41) | MAOBMAOAHTR2CHTR2AHTR2B | |
| SCHEMBL9540473 | 0.68 | HTR2C (0.50) | MAOBHTR2CHTR2AHTR2BSLC6A3 | |
| SCHEMBL9543103 | 0.67 | SLC6A2 (0.49) | MAOBHTR2CHTR2AHTR2BSLC6A3 | |
| SCHEMBL31417180 | 0.65 | SLC6A3 (0.58) | MAOBMAOASLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015100-A1 | NOVEL ADENOSINE DERIVATIVES, THEIR PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES UPSA (FR) | 1993-08-05 | — | — | WO | disclosed |
| US-5219839-A | Analgesics; anticonvulsant and -epileptic agents; antidepressants; anxiolytic, antiarrhythmic and hypotensive agents; anticoagulants | LABORATORIES UPSA (FR) | 1993-06-15 | — | — | US | disclosed |