Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541908 | 0.85 | MAOB (0.58) | SLC6A2SLC6A4HTR2CHTR2AHTR2B | |
| SCHEMBL9540473 | 0.73 | HTR2C (0.50) | SLC6A2SLC6A4HTR2CHTR2AHTR2B | |
| SCHEMBL9542009 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1OPRL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9541943 | 0.67 | MAOB (0.48) | SLC6A2SLC6A4HTR2CHTR2AHTR2B | |
| SCHEMBL15822840 | 0.67 | DPP4 (0.61) | SLC6A2SLC6A4MAOBOPRL1SLC6A3 | |
| SCHEMBL30467209 | 0.67 | DPP4 (0.61) | SLC6A2SLC6A4MAOBOPRL1SLC6A3 | |
| SCHEMBL21834929 | 0.66 | PTGS2 (0.41) | HTR2CHTR2AHTR2BMAOBALDH1A1 | |
| SCHEMBL20747663 | 0.66 | PTGS2 (0.41) | HTR2CHTR2AHTR2BMAOBALDH1A1 | |
| SCHEMBL6264514 | 0.66 | MAOB (0.40) | HTR2CHTR2AHTR2BMAOBLMNA | |
| SCHEMBL16198410 | 0.66 | MAOA (0.59) | SLC6A2SLC6A4MAOBOPRL1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015100-A1 | NOVEL ADENOSINE DERIVATIVES, THEIR PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES UPSA (FR) | 1993-08-05 | — | — | WO | disclosed |
| US-5219839-A | Analgesics; anticonvulsant and -epileptic agents; antidepressants; anxiolytic, antiarrhythmic and hypotensive agents; anticoagulants | LABORATORIES UPSA (FR) | 1993-06-15 | — | — | US | disclosed |