Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 3/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.65 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.65 |
| ▸ | SHBG | P04278 | 3/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MGAM | O43451 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427282 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL27607786 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL4572602 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL27248784 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL1651202 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL24151978 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL19877200 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| SCHEMBL1962644 | 1.00 | AKR1B10 (0.65) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| Propionic Acid SCHEMBL12694801 | 0.91 | GPBAR1 (0.57) | AKR1B10AKR1B1CYP19A1OR51E2SHBG | |
| Stanolone SCHEMBL11325499 | 0.91 | SHBG (0.82) | AKR1B10AKR1B1CYP19A1OR51E2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |
| US-4071625-A | 19-Oxygenated-5α-androstanes for the enhancement of libido | RICHARDSON-MERRELL INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3941811-A | Oxidation process | ROUSSEL-UCLAF (FR) | 1976-03-02 | — | — | US | disclosed |