Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EPOR | P19235 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437265 | 0.94 | LMNA (0.45) | LMNAKDM4EEPORL3MBTL1HPGD | |
| SCHEMBL9437271 | 0.94 | LMNA (0.47) | LMNAKDM4EEPORL3MBTL1HPGD | |
| SCHEMBL9437264 | 0.92 | LMNA (0.43) | LMNAKDM4EEPORL3MBTL1HPGD | |
| SCHEMBL9541992 | 0.90 | LMNA (0.45) | LMNAKDM4EEPORL3MBTL1HPGD | |
| SCHEMBL9437275 | 0.89 | L3MBTL1 (0.59) | LMNAKDM4EEPORL3MBTL1HPGD | |
| SCHEMBL9553247 | 0.89 | L3MBTL1 (0.59) | LMNAKDM4EEPORL3MBTL1HPGD | |
| SCHEMBL9542759 | 0.87 | L3MBTL1 (0.42) | LMNAL3MBTL1 | |
| SCHEMBL23502347 | 0.83 | HTT (0.50) | EPORL3MBTL1HDAC1HDAC2HDAC8 | |
| SCHEMBL8863668 | 0.82 | L3MBTL1 (0.50) | EPORL3MBTL1HTT | |
| SCHEMBL9437255 | 0.82 | EPOR (0.46) | LMNAEPORL3MBTL1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254724-A | Method for synthesis of desferrioxamine B, analogs and homologs thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1993009088-A1 | IMPROVED METHOD FOR SYNTHESIS OF DESFERRIOXAMINE B, ANALOGS AND HOMOLOGS THEREOF | UNIVERSITY OF FLORIDA (US) | 1993-05-13 | — | — | WO | disclosed |