Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540758 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL3481105 | 0.75 | CYP19A1 (0.61) | CYP1A2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL31036289 | 0.75 | CYP19A1 (0.61) | CYP1A2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL2123393 | 0.72 | CYP19A1 (0.57) | CYP19A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6750905 | 0.71 | CYP19A1 (0.49) | CYP1A2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL1252366 | 0.70 | CCR2 (0.51) | CYP1A2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL23045577 | 0.70 | NOD2 (0.52) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL31383470 | 0.70 | NOD2 (0.52) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL5113851 | 0.70 | KMT2A (0.49) | CYP1A2CYP19A1MEN1KMT2AMAPT | |
| SCHEMBL2124481 | 0.70 | CYP19A1 (0.64) | CYP19A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010119-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |