Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.47 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455822 | 0.87 | MEN1 (0.55) | TDP1MAOBHSD11B1HSD11B2SMN1; SMN2 | |
| SCHEMBL3456937 | 0.84 | MAOB (0.57) | MAOBPOLBMEN1KMT2ASMPD1 | |
| SCHEMBL9540802 | 0.83 | TUBB1 (0.47) | TDP1HSD11B1HSD11B2SMN1; SMN2MCHR1 | |
| SCHEMBL3455018 | 0.82 | MEN1 (0.61) | MAOBMEN1KMT2A | |
| SCHEMBL3455720 | 0.82 | SMN1; SMN2 (0.54) | LMNAHPGDSMN1; SMN2POLBMEN1 | |
| Benzamide SCHEMBL3455410 | 0.81 | PARP10 (0.54) | LMNAMAOBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10454995 | 0.79 | KMT2A (0.64) | LMNAHPGDSMN1; SMN2MCHR1POLB | |
| SCHEMBL11406234 | 0.79 | KMT2A (0.64) | LMNAHPGDSMN1; SMN2MCHR1POLB | |
| SCHEMBL8738176 | 0.78 | MAOB (0.48) | MRGPRX4MAOBCYP2C19SMN1; SMN2SMPD1 | |
| SCHEMBL7040051 | 0.75 | ALDH1A1 (0.54) | LMNAHPGDHSD11B1HSD11B2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | claimed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | claimed |
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |