Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PTAFR | P25105 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001766 | 0.87 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2GAAPOLBNPC1 | |
| SCHEMBL10453335 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GAAHSD11B1HSD11B2 | |
| SCHEMBL6000394 | 0.86 | HPGD (0.53) | ALDH1A1SMN1; SMN2GAAHSD11B1HSD11B2 | |
| SCHEMBL8119724 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2GAAHSD11B1HSD11B2 | |
| SCHEMBL3455371 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GAAPOLBNPC1 | |
| SCHEMBL2575803 | 0.82 | MEN1 (0.51) | MEN1KMT2AF2 | |
| SCHEMBL8130980 | 0.81 | POLB (0.62) | ALDH1A1SMN1; SMN2GAAPOLBNPC1 | |
| SCHEMBL4488042 | 0.81 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2GAAPOLBNPC1 | |
| SCHEMBL95169 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GAAPOLBNPC1 | |
| SCHEMBL20460603 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GAAPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162788-A1 | Combination of MTP inhibitors or apoB-secretion inhibitors with fibrates for use as pharmaceuticals | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-08-28 | — | — | US | disclosed |
| US-20030073836-A1 | Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-04-17 | — | — | US | disclosed |
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162788-A1 | Combination of MTP inhibitors or apoB-secretion inhibitors with fibrates for use as pharmaceuticals | APOB, LIPC, MTPN | ALDH1A1 2713/4885SMN1; SMN2 3711/4885GAA 276/4885 |
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | ALDH1A1 190/4885SMN1; SMN2 4752/4885GAA 1365/4885 |
| US-20030073836-A1 | Heteroarylcarboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | MTTP, CETP, CES1 | ALDH1A1 756/4885SMN1; SMN2 4795/4885GAA 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.