Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31439101 | 0.92 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL31439102 | 0.92 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9395642 | 0.92 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL27527236 | 0.78 | GRIA1 (0.57) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL29634290 | 0.78 | PGR (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL2718464 | 0.78 | PGR (0.60) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9542780 | 0.75 | SIRT2 (0.52) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8609548 | 0.75 | CYP1A2 (0.57) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL4980076 | 0.74 | SIRT2 (0.63) | GRIA1GRIA2GRIA3GRIA4SIRT2 | |
| SCHEMBL7349770 | 0.73 | GRIK1 (0.61) | GRIA1GRIA2GRIA3GRIA4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993008173-A1 | QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | claimed |
| WO-1993008173-A1 | QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | disclosed |