Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759902 | 0.92 | PAOX (0.61) | PAOXALDH1A1TSHRTDP1CYP2C19 | |
| SCHEMBL28194422 | 0.88 | TSHR (0.62) | PAOXALDH1A1TSHRTDP1CYP2C19 | |
| SCHEMBL14943786 | 0.87 | PAOX (0.62) | PAOXALDH1A1TSHRTDP1CYP2C19 | |
| SCHEMBL7994712 | 0.87 | PAOX (0.57) | PAOXALDH1A1TSHRTDP1CYP2C19 | |
| SCHEMBL29286457 | 0.86 | PAOX (0.61) | PAOXALDH1A1TSHRCYP2C19CHRM2 | |
| SCHEMBL28141910 | 0.86 | PAOX (0.61) | PAOXALDH1A1TSHRCYP2C19CHRM2 | |
| SCHEMBL10437484 | 0.85 | TSHR (0.43) | PAOXALDH1A1TSHRTDP1CYP2C19 | |
| SCHEMBL21067729 | 0.85 | TDP1 (0.50) | PAOXALDH1A1TSHRTDP1CYP2C19 | |
| SCHEMBL6656746 | 0.84 | PAOX (0.59) | PAOXALDH1A1TSHRTDP1CYP2C19 | |
| SCHEMBL759447 | 0.84 | PAOX (0.59) | PAOXALDH1A1TSHRTDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270310-A | N-aminoalkyl amide inhibitors of protein kinase C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-12-14 | — | — | US | disclosed |
| WO-1993011758-A1 | N-AMINOALKYL AMIDE INHIBITORS OF PROTEIN KINASE C | SPHINX PHARMACEUTICALS CORPORATION (US) | 1993-06-24 | — | — | WO | disclosed |