Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CASP2 | P42575 | 2/20 | 0.41 |
| ▸ | F13A1 | P00488 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056125 | 0.86 | PAOX (0.42) | TDP1PAOXCA12CA2CA4 | |
| SCHEMBL5518322 | 0.86 | ALOX15 (0.54) | TDP1PAOXCA12CA2CA4 | |
| SCHEMBL323710 | 0.85 | TDP1 (0.61) | TDP1PAOXCA12CA2CA4 | |
| SCHEMBL9542393 | 0.85 | PAOX (0.55) | TDP1PAOXCYP1A2CYP2C19MEN1 | |
| SCHEMBL427900 | 0.83 | TDP1 (0.59) | TDP1PAOXCA12CA2CA4 | |
| SCHEMBL4562189 | 0.83 | PAOX (0.55) | TDP1PAOXCA12CA2CA4 | |
| SCHEMBL26448079 | 0.83 | TDP1 (0.66) | TDP1PAOXCA12CA2CA4 | |
| SCHEMBL4562850 | 0.83 | PAOX (0.53) | TDP1PAOXCA12CA2CA4 | |
| SCHEMBL4562729 | 0.82 | PAOX (0.58) | TDP1PAOXCA12CA2CA4 | |
| Hydrochloric Acid SCHEMBL6114403 | 0.82 | UBE2N (0.58) | TDP1PAOXCA12CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| EP-3524614-A1 | COMPOUNDS WEAKENING SAICAR SYNTHASE ACTIVITY, AND APPLICATIONS | Geneheal Biotechnology Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |