SCHEMBL9542576

SCHEMBL9542576

Cc1nc2ccccc2c2sc(C(O)=S)c(OCC#N)c12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NMT2 O60551 1/20 0.34
NMT1 P30419 1/20 0.34
KMT2A Q03164 3/20 0.33
SMN1; SMN2 Q16637 5/20 0.33
ALDH1A1 P00352 4/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HTT P42858 1/20 0.33
GPR3 P46089 1/20 0.33
TLR8 Q9NR97 4/20 0.32
TLR7 Q9NYK1 4/20 0.32
PKM P14618 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
PDE10A Q9Y233 2/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
NUDT1 P36639 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9542558 0.75 PTPN2 (0.38) NMT2NMT1KMT2AALDH1A1L3MBTL1
SCHEMBL9540900 0.69 KDM4E (0.41) KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL9542448 0.63 MAPT (0.35) KMT2ASMN1; SMN2ALDH1A1L3MBTL1HTT
SCHEMBL9542450 0.61 KDM4E (0.43) KMT2ASMN1; SMN2ALDH1A1NPC1RAB9A
SCHEMBL6652136 0.60 PTPN2 (0.52) NMT1KMT2AALDH1A1KDM4EMAPK1
SCHEMBL23743154 0.57 MAPT (0.59) KMT2AALDH1A1KDM4EMAPK1CYP1A2
SCHEMBL24052764 0.56 TLR8 (0.72) ALDH1A1TLR8TLR7KDM4EHPGD
SCHEMBL11809546 0.56 KCNH2 (0.42) KMT2ASMN1; SMN2ALDH1A1L3MBTL1HTT
SCHEMBL21537700 0.56 GPR3 (0.65) SMN1; SMN2ALDH1A1HTTGPR3KDM4E
SCHEMBL1825131 0.56 SCN4A (0.47) KMT2AALDH1A1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993013664-A2 BIHETEROCYCLIC FUNGICIDAL COMPOUNDS SCHERING AGROCHEMICALS LIMITED (GB) 1993-07-22 WO disclosed