SCHEMBL24052764

SCHEMBL24052764

CCCc1nc2c(C)nc3ccccc3c2s1

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 18/20 0.72
TLR7 Q9NYK1 13/20 0.72
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
MAPT P10636 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373816 0.84 TLR8 (1.00) TLR8TLR7
SCHEMBL482958 0.84 TLR8 (1.00) TLR8TLR7
Hydrochloric Acid SCHEMBL5765916 0.83 TLR8 (0.97) TLR8TLR7
SCHEMBL24052314 0.82 TLR8 (0.73) TLR8TLR7KDM4EALDH1A1GAA
SCHEMBL26100478 0.80 TLR8 (0.83) TLR8TLR7MAPTNPSR1
SCHEMBL25627708 0.79 TLR8 (0.69) TLR8TLR7MAPTNPSR1
SCHEMBL6630084 0.79 TLR8 (0.63) TLR8TLR7KDM4EALDH1A1GAA
SCHEMBL25628534 0.79 TLR8 (0.69) TLR8TLR7MAPTNPSR1
SCHEMBL1528149 0.76 TLR8 (1.00) TLR8TLR7
SCHEMBL1527936 0.75 TLR8 (1.00) TLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021237055-A1 FUNCTIONAL LIPID DERIVATIVES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2021-11-25 WO disclosed