Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28863287 | 0.98 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2BRD4TAAR1 | |
| SCHEMBL17949098 | 0.87 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL21789041 | 0.84 | POLB (0.51) | NPC1SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL12832038 | 0.84 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2BRD4TAAR1 | |
| SCHEMBL30016228 | 0.82 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2BRD4TAAR1 | |
| SCHEMBL4461404 | 0.82 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2BRD4TAAR1 | |
| Hydrochloric Acid SCHEMBL8763040 | 0.80 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2BRD4TAAR1 | |
| SCHEMBL2222434 | 0.79 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2BRD4TAAR1 | |
| SCHEMBL5322964 | 0.78 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2BRD4TAAR1 | |
| SCHEMBL13350881 | 0.78 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2BRD4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |