Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.62 |
| ▸ | PGR | P06401 | 2/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.47 |
| ▸ | BLM | P54132 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542595 | 0.88 | SHBG (0.47) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9542813 | 0.85 | SHBG (0.46) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9544741 | 0.84 | SHBG (0.44) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9542430 | 0.84 | SHBG (0.45) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9543737 | 0.83 | SHBG (0.62) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9544771 | 0.83 | SHBG (0.43) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9543799 | 0.83 | SHBG (0.43) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9541905 | 0.82 | SHBG (0.70) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9125173 | 0.81 | SHBG (0.52) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL9125165 | 0.81 | SHBG (0.52) | SHBGALDH1A1NR3C1PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | claimed |
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |