Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 8/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542643 | 1.00 | SHBG (0.64) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL9543738 | 0.83 | SHBG (0.71) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL9541936 | 0.83 | SHBG (0.71) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL9543737 | 0.83 | SHBG (0.62) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| SCHEMBL9541286 | 0.79 | SHBG (0.49) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| Bolasterone SCHEMBL11876760 | 0.79 | SHBG (1.00) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| Calusterone SCHEMBL4509 | 0.79 | SHBG (1.00) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| Bolasterone SCHEMBL145066 | 0.79 | SHBG (1.00) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| Bolasterone SCHEMBL10904938 | 0.79 | SHBG (1.00) | SHBGALDH1A1CYP19A1ARNR3C1 | |
| Bolasterone SCHEMBL4945157 | 0.79 | SHBG (1.00) | SHBGALDH1A1CYP19A1ARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | claimed |
| WO-1993013122-A1 | 3-METHYLSULPHONYLHYDRAZONO AND 3-OXYIMINO STEROIDS, A METHOD OF PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |