Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16327606 | 0.60 | L3MBTL1 (0.47) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL9545716 | 0.57 | — | — | |
| SCHEMBL6388210 | 0.57 | NPC1 (0.44) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL15632425 | 0.55 | NPSR1 (0.37) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL5476941 | 0.55 | BRD4 (0.41) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL22175541 | 0.53 | CRBN (0.30) | — | |
| SCHEMBL9613513 | 0.53 | — | — | |
| SCHEMBL10155509 | 0.52 | CA12 (0.61) | — | |
| SCHEMBL12795884 | 0.52 | L3MBTL1 (0.52) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL715894 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552462-A1 | Thiadiazinecarboxamides, process for their preparation and pharmaceuticals | LUITPOLD PHARMA GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| WO-1993012119-A1 | THIADIAZINE CARBOXYLIC ACID AMIDE DERIVATIVES, METHODS OF PREPARING THEM AND DRUGS CONTAINING THEM | LUITPOLD PHARMA GMBH (DE) | 1993-06-24 | — | — | WO | disclosed |