SCHEMBL95433

SCHEMBL95433

[CH]=CC=Cc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.68
MAPK1 P28482 2/20 0.56
ALDH1A1 P00352 2/20 0.56
LMNA P02545 2/20 0.56
TRPA1 O75762 2/20 0.56
ALOX5 P09917 1/20 0.56
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
MAPT P10636 2/20 0.46
RECQL P46063 2/20 0.46
POLB P06746 1/20 0.46
CMA1 P23946 1/20 0.45
NFE2L2 Q16236 2/20 0.44
CYP19A1 P11511 1/20 0.44
MAOA P21397 1/20 0.44
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95432 1.00 MAOB (0.68) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL96922 0.90 MAOB (0.70) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL96921 0.90 MAOB (0.70) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL27571915 0.87 MAOB (0.67) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL23458007 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL592744 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL5875512 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
SCHEMBL6853572 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
Benzene SCHEMBL9803304 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1
Benzene SCHEMBL135524 0.82 MAOB (1.00) MAOBMAPK1ALDH1A1LMNATRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920636-B Synthesis method of alpha chloro-aryl-ethanone compound 东南大学 2023-12-22 CN claimed
CN-113831272-B Method for synthesizing 2-substituted indole compound by palladium-catalyzed iodobenzene and oxime ester 华南理工大学 2023-07-18 CN claimed
CN-114920636-A Synthetic method of alpha chloro arylethanone compound 东南大学 2022-08-19 CN claimed
CN-113831272-A Method for synthesizing 2-substituted indole compound by using palladium to catalyze iodobenzene and oxime ester 华南理工大学 2021-12-24 CN claimed
CN-112534356-A Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2021-03-19 CN claimed
EP-0885192-B8 DIHYDROPYRIDINE-, PYRIDINE-, BENZOPYRAN- ONE- AND TRIAZOLOQUINAZOLINE DERIVATIVE, THEIR PREPARATION AND THEIR USE AS ADENOSINE RECEPTOR ANTAGONISTS US OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) 2012-05-16 EP claimed
EP-2311806-A2 Dihydropyridine-, pyridine-, benzopyranone- and triazoloquinazoline derivatives, their preparation and their use as adenosine receptor antagonists The United States of America, Represented by the Secretary, Department of Health and Human Services (US) 2011-04-20 EP claimed
US-20070092551-A1 Therapeutic agent TAKARA BIO INC. (JP) 2007-04-26 US claimed
EP-1623704-A1 THERAPEUTIC AGENT TAKARA BIO INC. (JP) 2006-02-08 EP claimed
EP-0670041-B1 FLUORESCENCE ENERGY TRANSFER AND INTRAMOLECULAR ENERGY TRANSFER IN PARTICLES USING NOVEL COMPOUNDS BIOSITE DIAGNOSTICS INC (US) 2002-01-30 EP claimed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP claimed
US-4738908-A AQULENIUM SALT CANON KABUSHIKI KAISHA (JP) 1988-04-19 US claimed
US-4673630-A Photoconductive film and electrophotographic photosensitive member contains azulenium salt CANON KABUSHIKI KAISHA (JP) 1987-06-16 US claimed
US-4629670-A INFRARED RADIATION SENSITIVITY CANON KABUSHIKI KAISHA (JP) 1986-12-16 US claimed
US-4548886-A ELECTROGRAPHIC FILMS; OPTICAL RECORDING MEDIA CANON KABUSHIKI KAISHA (JP) 1985-10-22 US claimed
EP-0139614-A2 Pharmaceutical preparations containing flavanone or thioflavanone derivatives, the use thereof, novel flavanones and thioflavanones, and processes for their manufacture Zyma SA (CH) 1985-05-02 EP claimed
US-4206142-A REACTING A STYRYLSULFONYLAMIDINE WITH A BASE MEAD JOHNSON & COMPANY (US) 1980-06-03 US claimed
US-4130663-A ANTITHROMBOGENIC, ANTIHYPERTENSIVE MEAD JOHNSON & COMPANY (US) 1978-12-19 US claimed
US-4096183-A Styrylsulfonylamidines MEAD JOHNSON & COMPANY (US) 1978-06-20 US claimed
US-4052455-A ANALGESICS, BLOOD PLATELET AGGREGATION INHIBITORS MEAD JOHNSON & COMPANY (US) 1977-10-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070092551-A1 Therapeutic agent FABP4, GPR119, IAPP MAOB 4382/4885MAPK1 1311/4885ALDH1A1 951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.