SCHEMBL9543365

SCHEMBL9543365

N=NN(c1ccccc1)c1nc(Cl)c(C=O)s1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.47
MAPT P10636 5/20 0.47
KMT2A Q03164 5/20 0.47
LMNA P02545 3/20 0.47
PSMD14 O00487 1/20 0.47
ALDH1A1 P00352 4/20 0.38
GLA P06280 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8743006 0.79 MEN1 (0.50) MEN1MAPTKMT2ALMNAPSMD14
SCHEMBL25691021 0.70 ALDH1A1 (0.59) MEN1MAPTKMT2ALMNAPSMD14
SCHEMBL29953786 0.69 ALDH1A1 (0.42) MEN1MAPTKMT2ALMNAPSMD14
SCHEMBL11311306 0.68 NPC1 (0.47) MEN1MAPTKMT2ALMNAALDH1A1
SCHEMBL15156345 0.68 MEN1 (0.41) MEN1MAPTKMT2ALMNAPSMD14
SCHEMBL29956125 0.67 MEN1 (0.55) MEN1MAPTKMT2ALMNAPSMD14
SCHEMBL8829009 0.66 ALDH1A1 (0.55) MEN1MAPTKMT2AALDH1A1L3MBTL1
SCHEMBL15332354 0.64 MEN1 (0.39) MEN1MAPTKMT2ALMNAPSMD14
SCHEMBL29956897 0.64 KMT2A (0.55) MEN1MAPTKMT2ALMNAPSMD14
SCHEMBL15331855 0.64 MAPT (0.51) MEN1MAPTKMT2ALMNAPSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993010978-A1 METHOD OF MAKING A MONOCHROMIC COLOURED THERMAL DYE IMAGE AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1993-06-10 WO claimed
WO-1993010978-A1 METHOD OF MAKING A MONOCHROMIC COLOURED THERMAL DYE IMAGE AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1993-06-10 WO disclosed