Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | CD81 | P60033 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029825 | 0.82 | APLNR (0.44) | APLNRFFAR3GRM4CYP2C19ALDH1A1 | |
| SCHEMBL12359651 | 0.82 | APLNR (0.44) | APLNRFFAR3GRM4CYP2C19ALDH1A1 | |
| SCHEMBL2251075 | 0.82 | APLNR (0.44) | APLNRFFAR3GRM4CYP2C19ALDH1A1 | |
| SCHEMBL2968328 | 0.82 | APLNR (0.44) | APLNRFFAR3GRM4CYP2C19ALDH1A1 | |
| SCHEMBL960182 | 0.75 | SMN1; SMN2 (0.36) | APLNRFFAR3GRM4CYP2C19ALDH1A1 | |
| SCHEMBL4296033 | 0.75 | LMNA (0.44) | APLNRCYP2C19ALDH1A1CYP1A2MEN1 | |
| Bicarbonate SCHEMBL11398445 | 0.74 | APLNR (0.40) | APLNRFFAR3CD81CYP2C19MAPK1 | |
| SCHEMBL25330082 | 0.73 | — | — | |
| SCHEMBL19557132 | 0.73 | — | — | |
| SCHEMBL5314714 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012138-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING HIV INFECTIONS | SCHERING CORPORATION (US) | 1993-06-24 | — | — | WO | disclosed |