Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.59 |
| ▸ | FEN1 | P39748 | 2/20 | 0.59 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TNKS | O95271 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29331815 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL8677247 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL12487999 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL5821314 | 0.73 | KDM4E (0.48) | SMN1; SMN2ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL15931704 | 0.73 | TSHR (0.58) | SMN1; SMN2KDM4EMAPTTDP1LMNA | |
| SCHEMBL7901099 | 0.71 | MAPT (0.48) | SMN1; SMN2ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL8380313 | 0.71 | HPGD (0.65) | KDM4EMAPTTDP1LMNAALDH1A1 | |
| SCHEMBL25138647 | 0.70 | SMN1; SMN2 (0.66) | SMN1; SMN2ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL4607219 | 0.69 | ERCC1 (0.56) | SMN1; SMN2ERCC1FEN1ERCC4KDM4E | |
| SCHEMBL22372656 | 0.69 | POLB (0.62) | SMN1; SMN2ERCC1FEN1ERCC4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |