Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 4/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380313 | 0.74 | HPGD (0.65) | MAPTKDM4ETDP1XDHMEN1 | |
| SCHEMBL9543700 | 0.71 | SMN1; SMN2 (0.64) | MAPTKDM4ETDP1XDHMEN1 | |
| SCHEMBL7900996 | 0.68 | TSHR (0.48) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL7496014 | 0.65 | POLB (0.72) | MAPTKDM4EXDHMEN1KMT2A | |
| SCHEMBL7899634 | 0.65 | MEN1 (0.45) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL8676878 | 0.64 | POLB (0.64) | MAPTKDM4EXDHMEN1KMT2A | |
| SCHEMBL258433 | 0.63 | TNKS (1.00) | MAPTKDM4ETNKSTNKS2PARP1 | |
| SCHEMBL29592833 | 0.63 | TNKS (1.00) | MAPTKDM4ETNKSTNKS2PARP1 | |
| SCHEMBL8677297 | 0.63 | POLB (0.50) | MAPTKDM4EXDHMEN1KMT2A | |
| SCHEMBL8677311 | 0.63 | POLB (0.50) | MAPTKDM4EXDHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221103-A1 | New heterocyclic compounds | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221103-A1 | New heterocyclic compounds | LOXL4, CXCR4, LTC4S | MAPT 699/4885KDM4E 1998/4885TDP1 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.