Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 5/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364441 | 0.67 | HPRT1 (0.60) | PNPHPRT1 | |
| SCHEMBL9545341 | 0.64 | PNP (0.35) | PNPBACE1MEN1KMT2ATYMS | |
| SCHEMBL1586365 | 0.64 | PNP (0.37) | PNPHPRT1 | |
| Hydrochloric Acid SCHEMBL9544734 | 0.63 | DHFR (0.35) | PNPBACE1TYMSHPRT1 | |
| SCHEMBL12958940 | 0.63 | PNP (0.36) | PNPXDHHPRT1 | |
| Hydrochloric Acid SCHEMBL9545280 | 0.62 | HPRT1 (0.34) | PNPBACE1XDHMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9544813 | 0.62 | PNP (0.34) | PNPBACE1MEN1KMT2AHPRT1 | |
| Hydrochloric Acid SCHEMBL9544122 | 0.62 | PNP (0.34) | PNPBACE1HPRT1 | |
| SCHEMBL12958946 | 0.62 | PNP (0.36) | PNPBACE1XDHMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9544004 | 0.61 | DHFR (0.38) | PNPMEN1KMT2AHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020075-A1 | 8-SUBSTITUTED-N5-DEAZAPTERINS AS ANTIFOLATES | THE UNIVERSITY OF SYDNEY (AU) | 1993-10-14 | — | — | WO | disclosed |