Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.61 |
| ▸ | PPARG | P37231 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544644 | 0.95 | PPARA (0.59) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9544551 | 0.95 | PPARA (0.59) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9544528 | 0.95 | PPARA (0.59) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL7757498 | 0.91 | PPARA (0.56) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL7757490 | 0.89 | SIRT2 (0.55) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL7757493 | 0.88 | PPARA (0.53) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL7708741 | 0.87 | PPARA (0.53) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL5507111 | 0.87 | PPARA (0.53) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL23927277 | 0.87 | PPARA (0.73) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL21957907 | 0.86 | PPARA (0.65) | PPARAPPARGHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021211-A1 | AMIDES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATORIOS MENARINI S.A. (ES) | 1993-10-28 | — | — | WO | disclosed |